The Power to See More in High-Throughput Slide Imaging
High-volume slide imaging benefits a range of areas in life science research. Examples include structure, connectivity and activity analysis in neuroscience, cell morphology and protein localization in cancer and stem cell research, and toxicity studies and drug screening in pharmaceutical and biotech research. It can be challenging to find a single high-throughput scanner to cater for all these different applications – and one that is also easy-to-use and consistently delivers high image quality.
Discover Flexible Slide Scanning
The Olympus Slideview VS200 (fig. 1) is a flexible solution for high-throughput slide scanning. It has five different observation methods – brightfield, fluorescence, darkfield, phase contrast and polarized light – and can automatically handle a mixture of slide sizes from 26 × 76 mm to 102 × 127 mm. Fluorescence multiplexing is supported, which makes it possible to create images based on eight or more channels. Fluorescence multiplexing is an increasingly common method of phenotyping cells, for example identifying types of T cells at tumor sites.
Outstanding Image Quality, Reliable Quantification
For crisp, analysis-ready images, the VS200 captures every detail in every slide across all five observation methods. The optical path has been designed specifically for slide scanners and incorporates Olympus’ new X Line objectives, which overcome the trade-off between resolution, image flatness and color accuracy – delivering improvements in all three (fig. 2). This means researchers can get the most out of their slides. Alongside the optics, the improved stability and accurate focus of the VS200 gives users greater confidence when scanning slides and quantifying images.
A Fluid Workflow for Every User
The VS200 is designed for users of all levels. The basic operation mode enables users to acquire images in as little as two clicks, while the expert mode gives experienced users full control, allowing them to set all parameters and assign custom settings to different imaging projects. This is particularly useful if an imaging project requires imaging different sets of slides over a long timeframe.
For improved ease of use, the VS200 has a robototic automated slide loader that can handle up to 210 slides while mixing slide sizes. The hot-swap function allows users to change slides during scanning in case of urgent needs. To enable efficient working, the VS200 makes it possible to edit scanned images in parallel with ongoing scans. An automated barcode reader provides reliable capture and recording of information about each slide.
Figure 1. Olympus’ Slideview VS200 is well suited for high-throughput slide scanning in a wide range of research applications
Figure 2. X Line objectives within the Olympus Slideview VS200 automated slide scanner ensure image flatness across whole brain slices. 10x magnification, 300 dpi.
Elevate your Slide Imaging
Olympus’ flexible Slideview VS200 simplifies high-throughput slide imaging, enabling researchers to see more of their slides with best-in-class optics. Five observation modes and four slide sizes enable the VS200 to support a range of research applications, while different workflows ensure efficient operation for both beginners and expert users.