Bruker launches 'highest resolution' large-format Bio-AFM system


Rebecca Pool

Wednesday, September 4, 2019 - 13:15
Image: Large-format Bio-AFM from Bruker
Bruker has released the NanoWizard 4 XP extreme performance Bio-AFM system.
The new system integrates Bruker's PeakForce Tapping, which promises both superior force control and unparalleled AFM ease of use, and QI mode for high-resolution nanomechanics on soft samples.
Building on JPK's pioneering role in combining AFM with advanced optical techniques, the NanoWizard 4 XP system is said to provide highest level correlative microscopy and seamless integration with phase, DIC, confocal or spinning disc microscopies, single-molecule methods (FRET, FCS, TIRF, FLIM, FRAP), super-resolution techniques (STED, PALM/STORM, SIM), Raman, and multiphoton microscopy.
"We have found PeakForce Tapping a most robust way of achieving high-resolution AFM on a variety of biological samples," says Bart Hoogenboom, Professor of Biophysics at London Centre for Nanotechnology, University College London, UK.
"We are therefore glad to see that it is now also implemented on the NanoWizard systems... to achieve similarly high imaging performance on platforms that are compatible with inverted optical microscopy," he adds.
In addition to PeakForce Tapping and QI mode, the NanoWizard 4 XP comes with JPK's next-generation Vortis 2 high-speed, high-performance control electronics.
Vortis 2 delivers the lowest noise levels and highest signal processing speeds, and it is designed to meet the needs of all operator experience levels.
A new workflow-based software GUI includes guidance, auto-setup, and workspace organization to deliver results quickly and to enhance productivity.
As an option, NestedScanner technology enables an AFM scanning speed of 150 lines per second, said to be unprecedented for a large-scanner system, while maintaining access to any location within all three axes.
Researchers have full access to follow dynamics wherever the sample takes them, offering a true synergy with simultaneous optical microscopy.
"Since becoming part of Bruker one year ago, we have continued to collaborate closely with our worldwide user base to develop the cutting-edge biological AFM and optical tweezers technologies that our customers need for advanced research," says Torsten Jaehnke, Bruker's Director of BioAFM. "With the new NanoWizard 4 XP system, we have once again set a performance benchmark for atomic force microscopy in life science research."
Learn more here.
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